Southwest Illinois Vacations from $266
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Your Southwest Illinois Vacation
When it's time for your next epic adventure, our Southwest Illinois vacation packages are the answer. Culture and history are among the many things that make this destination such a special place. Begin your trip to Southwest Illinois with some time exploring O'Fallon visiting popular sights like O'Fallon Family Sports Park and FanDuel Sportsbook and Horse Racing. Marion is another city that lures travelers from all over. Lake of Egypt and Crab Orchard National Wildlife Refuge are two of the top places to see in this destination. From the moment you book your Southwest Illinois vacation to the second you come back home, Expedia will be with you each step of the way.
The Latest Southwest Illinois vacation packages
Price found within the past 48 hours. Click for updated prices.
The Royal Sonesta Chase Park Plaza St. Louis
Central West End
$317
per person
Nov 13 - Nov 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,014 reviews)
Excellent Hotel in a Perfect Location
I had a wonderful stay at The Royal Sonesta Chase Park Plaza St. Louis. The location is excellent, especially if you need to visit Washington University or explore the Central West End. One of the best things about the hotel is that it is right across from Forest Park, a beautiful and enormous park where you can walk for a very long time and enjoy the scenery. The surrounding streets are also beautiful, clean, and pleasant to walk around.
The hotel itself is beautiful and has a classic, elegant atmosphere. The staff were extremely friendly, welcoming, and helpful throughout my stay. I was also pleasantly surprised to receive a complimentary room upgrade with no additional charge.
My upgraded room was very clean, spacious, comfortable, and had a great view. Everything about the stay felt comfortable and well taken care of.
I would highly recommend it to anyone visiting St. Louis!
Reviewed on Oct 5, 2026
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See all available trips from Columbus to Southwest Illinois
View all tripsWhere to stay in Southwest Illinois
Find the best Southwest Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southwest Illinois
Eastport
If you're spending some time in Eastport, Splash City Family Waterpark and Gateway Conference Center are top sights worth seeing.
Mulberry Hills
While Mulberry Hills isn't home to many top sights, World's Largest Catsup Bottle and Kruta Bakery are some notable places to visit nearby.
Uptown
If you're spending some time in Uptown, Kruta Bakery and World's Largest Catsup Bottle are top sights worth seeing.
Alorton
Alorton is well-liked for its restaurants. If you'd like to do some sightseeing in the greater East St. Louis area, you might plan a trip to Frank Holten State Recreation Area or Arsenal BG Ballpark.
Historic Downtown Collinsville
While Historic Downtown Collinsville isn't home to many top sights, World's Largest Catsup Bottle and Kruta Bakery are some notable places to visit nearby.
Stay near popular Southwest Illinois attractions
Giant City State Park
9.2/10 (141 reviews)
Walk amid mystical woodland, admire geological wonders, go horseback riding and camp in the wilderness in the spectacular countryside of Southwest Illinois.
World Wide Technology Raceway
9.0/10 (2 reviews)
Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
O'Fallon Family Sports Park
8.6/10 (137 reviews)
Explore the great outdoors at O'Fallon Family Sports Park, a lovely green space in O'Fallon. Check out the shops and top-notch restaurants in this family-friendly area.
DuQuoin State Fairgrounds
8.2/10 (95 reviews)
Catch an event at DuQuoin State Fairgrounds during your trip to Du Quoin. Experience the area's festivals and live music.
Southwest Illinois Hotel Deals
Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$90 nightly
$102 total
Nov 1 - Nov 2
Total with taxes and fees
Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$111 nightly
$125 total
Oct 11 - Oct 12
Total with taxes and fees
Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
$102 nightly
$118 total
Oct 11 - Oct 12
Total with taxes and fees
9.6/10 Exceptional! (1,005 reviews)
"Great staff and clean room"
Reviewed on Oct 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Southwest Illinois Vacation Packages
Southwest Illinois Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Lambert-St. Louis Intl. Airport (STL) |
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Frequently asked questions
What's included in a Southwest Illinois vacation package?
A Southwest Illinois vacation package in O'Fallon lets you combine flights, hotel stays, and rental cars. Most hotels in O'Fallon offer free breakfast, and some also provide airport shuttle service to St. Louis Lambert International Airport (STL). Exactly what's included will vary by hotel and package, so it's worth reviewing the details before you confirm your booking.
How can I save money on a Southwest Illinois vacation package?
When you bundle, you can save up to 30%*. To save money on a Southwest Illinois package, consider traveling during the quieter months or be flexible with your dates to find more options. Bundling your flights and hotel together often unlocks savings compared to booking separately. *Members only. Savings vary.
Which destinations should I consider for a Southwest Illinois vacation?
When planning a Southwest Illinois vacation, consider these destinations as your base, each offering a distinct travel style:
- Marion: A top choice for romantic getaways and outdoor adventures, known for its scenic views and a good selection of lodging.
- Carbondale: Ideal for travelers seeking romantic trips and active outdoor experiences, with many options for adventure activities.
- O'Fallon: Best suited for families and those interested in urban attractions, also offering outdoor activities and eco-friendly travel options.
- Edwardsville: A great base for family-friendly attractions and romantic escapes, combining outdoor activities with scenic surroundings.
Is Southwest Illinois better suited for a beach vacation or a cultural trip?
Southwest Illinois is primarily an outdoor and nature destination, known for its scenic views and adventure activities. Travelers can enjoy a wide range of outdoor pursuits, from exploring the waters of Lake of Egypt in Marion to hiking the unique geological formations at Giant City State Park near Carbondale.The region does offer cultural and historical experiences. Visitors can delve into ancient history at Cahokia Mounds State Historic Site near O'Fallon or enjoy local arts and events at the Marion Cultural and Civic Center. Your Southwest Illinois vacation can be customized around these diverse activities.
Which airport should I use for a Southwest Illinois vacation?
For a Southwest Illinois vacation, St. Louis Lambert International Airport (STL) in St. Louis, Missouri, serves as the primary gateway. Another convenient option is Evansville Regional Airport (EVV) in Evansville, Indiana. Both airports serve the wider Southwest Illinois region, with onward travel to your specific destination.
What are the top things to do in Southwest Illinois?
A Southwest Illinois vacation is best explored from a base like Marion, which offers a variety of outdoor activities and scenic views:Browse and book things to do in Southwest Illinois on Expedia.
Can I change or cancel my Southwest Illinois vacation package if my plans change?
Yes, you can cancel your vacation package via your itinerary page on Expedia or by contacting customer service. Remember that some packages are fully refundable, but the details vary based on each unique booking. A fully refundable package may depend on how far out from the travel dates you're canceling and what airline you are traveling with.
Do One Key members get extra savings when booking Southwest Illinois vacation packages?
Yes, members who join our free One Key™ travel rewards program can instantly unlock additional savings and save 10% or more on over 500,000 stays worldwide with Member Prices and over 1 million car rentals.
Does Expedia offer Book Now, Pay Later Southwest Illinois vacation packages?
Yes, with Expedia's Book Now, Pay Later option, powered by Affirm, you can spread the cost of your Southwest Illinois vacation over 3, 6, or 12 months. With no late payment fees or hidden costs, it's easy to secure your ideal vacation package as soon as you spot it.
How do I find last-minute vacation packages to Southwest Illinois?
To find last-minute vacation packages to Southwest Illinois, explore the last-minute deals section for the latest package offers, including flights, departing in the coming weeks. Being flexible with your travel dates and hotel preferences can help you secure the best prices.
How does free cancellation work on Southwest Illinois vacation packages?
Free cancellation on a Southwest Illinois vacation package depends on the specific hotel and rate combination you book. Many bookings allow free cancellation up to a stated deadline (often a few days before travel) where eligible. Read the cancellation terms carefully when reviewing the package, and visit Expedia help center for further details.
Is it cheaper to book a Southwest Illinois vacation as a package or separately?
An Expedia vacation package could land you great savings when compared to arranging flights and hotels separately. Better still, you can tailor your Southwest Illinois getaway to match your exact preference. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
Why should I book my Southwest Illinois vacation package with Expedia?
Booking your vacation package on Expedia makes it easier to get more out of your trip from the start. With a wide choice of hotels, you can compare prices, reviews and amenities all in one place, then bundle your hotel with flights which could help you save even more. Flexible booking options on selected stays also make it easier to plan with confidence.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
