Name: Drury Plaza Hotel Mt. Vernon
Price range: $115 total
Rating: 9.6

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Your Southwest Illinois Vacation

When it's time for your next epic adventure, our Southwest Illinois vacation packages are the answer. Culture and history are among the many things that make this destination such a special place. Begin your trip to Southwest Illinois with some time exploring O'Fallon visiting popular sights like O'Fallon Family Sports Park and FanDuel Sportsbook and Horse Racing. Marion is another city that lures travelers from all over. Lake of Egypt and Crab Orchard National Wildlife Refuge are two of the top places to see in this destination. From the moment you book your Southwest Illinois vacation to the second you come back home, Expedia will be with you each step of the way.

The Latest Southwest Illinois vacation packages

Price found within the past 48 hours. Click for updated prices.

The Wildwood Hotel

Save 100% on your flight

$598

per person

Jun 18 - Jun 21

found 14 hours ago

Roundtrip flight included

Boston (BOS) to St. Louis (STL)

9.2/10 Wonderful! (1,627 reviews)

The breakfaat was average, thou fresh. There was enough street parking nearby, safe.

Reviewed on Mar 30, 2026

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Grand Center

$616

per person

Jun 4 - Jun 7

found 1 day ago

Roundtrip flight included

Las Vegas (LAS) to St. Louis (STL)

8.8/10 Excellent! (1,049 reviews)

Everything was great! Hotel is beautiful, staff was so friendly, perfect trip!

Reviewed on Apr 6, 2026

DoubleTree by Hilton Hotel St. Louis - Chesterfield

$717

per person

Jun 4 - Jun 7

found 1 day ago

Roundtrip flight included

Las Vegas (LAS) to St. Louis (STL)

8.6/10 Excellent! (1,000 reviews)

Clean room, friendly & helpful staff, cook prepared omelette breakfast was yumyum. Really enjoyed our stay!

Reviewed on Apr 4, 2026

The Cheshire

$617

per person

Jun 18 - Jun 21

found 14 hours ago

Roundtrip flight included

Boston (BOS) to St. Louis (STL)

8.6/10 Excellent! (1,011 reviews)

It had unique decor which was fun. Staff was nice But the lights were broken and there was a leftover can under a chair

Reviewed on Apr 1, 2026

AC Hotel St. Louis Clayton

Clayton

$640

per person

Jun 4 - Jun 7

found 1 day ago

Roundtrip flight included

Las Vegas (LAS) to St. Louis (STL)

9/10 Wonderful! (268 reviews)

The property has been rated five stars. The location is desirable, parking facilities are ample, and the accommodations are meticulously maintained.

Reviewed on Mar 29, 2026

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Where to stay in Southwest Illinois

Find the best Southwest Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southwest Illinois

Aerial view of the iconic Gateway Arch and Mississippi River with urban skyline and bridges, Downtown St. Louis, Missouri, United States.

Eastport

If you're spending some time in Eastport, Gateway Conference Center and Splash City Family Waterpark are top sights worth seeing.

Discover the most popular places to visit in Southwest Illinois

Southern Illinois University

4.5/5(175 reviews)

Take a campus tour or just explore the area of Southern Illinois University, during your trip to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.

Giant City State Park

4.5/5(80 reviews)

Walk amid mystical woodland, admire geological wonders, go horseback riding and camp in the wilderness in the spectacular countryside of Southwest Illinois.

Ferne Clyffe State Park

4.5/5(10 reviews)

You can take time to visit Ferne Clyffe State Park during your travels to Goreville. While you're in the area, wander around the parks.

Southwest Illinois Hotel Deals

Drury Inn & Suites St. Louis Fairview Heights

12 Ludwig Dr Fairview Heights IL

Fully refundableReserve now, pay when you stay

$94 nightly

$106 total

Apr 16 - Apr 17

Total with taxes and fees

9.2/10 Wonderful! (1,012 reviews)

Great room great breakfast very clean.

Reviewed on Apr 9, 2026

Drury Inn & Suites St. Louis O'Fallon, IL

1118 Central Park Drive O'Fallon IL

Fully refundableReserve now, pay when you stay

$106 nightly

$123 total

May 3 - May 4

Total with taxes and fees

9.6/10 Exceptional! (1,002 reviews)

The free breakfast & appetizers/dinner is wonderful♥️ The staff all seem happy & positive♥️ Very clean♥️

Reviewed on Apr 6, 2026

Drury Plaza Hotel Mt. Vernon

145 North 44th Street Mount Vernon IL

Fully refundableReserve now, pay when you stay

$102 nightly

$115 total

Apr 19 - Apr 20

Total with taxes and fees

9.6/10 Exceptional! (1,663 reviews)

Checkin cas fast and room was clean

Reviewed on Apr 5, 2026

See all 752 properties in Southwest Illinois

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.