Name: Drury Plaza Hotel Mt. Vernon
Price range: $110 total
Rating: 9.6

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Your Southwest Illinois Vacation

When it's time for your next epic adventure, our Southwest Illinois vacation packages are the answer. Culture and history are among the many things that make this destination such a special place. Begin your trip to Southwest Illinois with some time exploring O'Fallon visiting popular sights like O'Fallon Family Sports Park and FanDuel Sportsbook and Horse Racing. Marion is another city that lures travelers from all over. Lake of Egypt and Crab Orchard National Wildlife Refuge are two of the top places to see in this destination. From the moment you book your Southwest Illinois vacation to the second you come back home, Expedia will be with you each step of the way.

The Latest Southwest Illinois vacation packages

Price found within the past 48 hours. Click for updated prices.

HoteLumiere at the Arch - A Caesars Rewards Destination

Downtown St. Louis

Save 100% on your flight

$273

per person

Jun 24 - Jun 27

found 10 hours ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

6.8/10 (1,000 reviews)

Staff was generally unfriendly, odd smell about the place

Reviewed on Apr 12, 2026

The Wildwood Hotel

$392

per person

Jun 24 - Jun 27

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

9.2/10 Wonderful! (1,627 reviews)

Poor quality breakfast buffet, unsecured parking, worn furnishings, in need of a redo. Overpriced for conditions.

Reviewed on Apr 17, 2026

The Cheshire

Save 100% on your flight

$296

per person

Jun 24 - Jun 27

found 10 hours ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

8.6/10 Excellent! (1,011 reviews)

Breakfast was very nice

Reviewed on Apr 17, 2026

Hilton Pennywell St. Louis at the Arch

Downtown St. Louis

Save 100% on your flight

$472

per person

Jun 24 - Jun 27

found 10 hours ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

8.8/10 Excellent! (1,030 reviews)

This hotel had a very elegant modern vibe while encapsulating the big city bustle, it was very convenient to the stadiums, the arch and the river. The only downfall which is not their fault is the dilapidated hotel right across the street, definitely an eyesore but hopefully the city will have an amazing opportunity to revitalize that area! But back to this idea hotel, it was very clean and comfortable!

Reviewed on Apr 15, 2026

Ameristar Casino Resort and Spa

Save 100% on your flight

$375

per person

Jun 24 - Jun 27

found 10 hours ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

8.4/10 Very Good! (1,003 reviews)

Enjoyed our stay. Clean facility

Reviewed on Apr 4, 2026

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Where to stay in Southwest Illinois

Find the best Southwest Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southwest Illinois

Aerial view of the iconic Gateway Arch and Mississippi River with urban skyline and bridges, Downtown St. Louis, Missouri, United States.

Eastport

If you're spending some time in Eastport, Gateway Conference Center and Splash City Family Waterpark are top sights worth seeing.

Discover the most popular places to visit in Southwest Illinois

Southern Illinois University

4.5/5(175 reviews)

Take a campus tour or just explore the area of Southern Illinois University, during your trip to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.

Giant City State Park

4.5/5(80 reviews)

Walk amid mystical woodland, admire geological wonders, go horseback riding and camp in the wilderness in the spectacular countryside of Southwest Illinois.

Ferne Clyffe State Park

4.5/5(10 reviews)

You can take time to visit Ferne Clyffe State Park during your travels to Goreville. While you're in the area, wander around the parks.

Southwest Illinois Hotel Deals

Drury Inn & Suites St. Louis Fairview Heights

12 Ludwig Dr Fairview Heights IL

Fully refundableReserve now, pay when you stay

$106 nightly

$120 total

May 6 - May 7

Total with taxes and fees

9.2/10 Wonderful! (1,003 reviews)

Clean room! Super friendly staff! Easy access and parking!

Reviewed on Apr 17, 2026

Drury Inn & Suites St. Louis O'Fallon, IL

1118 Central Park Drive O'Fallon IL

Fully refundableReserve now, pay when you stay

$104 nightly

$120 total

May 17 - May 18

Total with taxes and fees

9.6/10 Exceptional! (1,004 reviews)

Very friendly spacious and clean! Great people

Reviewed on Apr 16, 2026

Drury Plaza Hotel Mt. Vernon

145 North 44th Street Mount Vernon IL

Fully refundableReserve now, pay when you stay

$97 nightly

$110 total

Apr 26 - Apr 27

Total with taxes and fees

9.6/10 Exceptional! (1,674 reviews)

The room was quiet and had comfortable beds. The free snacks (5:30 - 7:00) were delicious and enough for a meal. Breakfast was also excellent :)

Reviewed on Apr 16, 2026

See all 755 properties in Southwest Illinois

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.