Name: Drury Inn & Suites St. Louis O'Fallon, IL
Price range: $123 total
Rating: 9.6

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Your Southwest Illinois Vacation

When it's time for your next epic adventure, our Southwest Illinois vacation packages are the answer. Culture and history are among the many things that make this destination such a special place. Begin your trip to Southwest Illinois with some time exploring O'Fallon visiting popular sights like O'Fallon Family Sports Park and FanDuel Sportsbook and Horse Racing. Marion is another city that lures travelers from all over. Lake of Egypt and Crab Orchard National Wildlife Refuge are two of the top places to see in this destination. From the moment you book your Southwest Illinois vacation to the second you come back home, Expedia will be with you each step of the way.

The Latest Southwest Illinois vacation packages

Price found within the past 48 hours. Click for updated prices.

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Grand Center

Save 100% on your flight

$264

per person

Jun 6 - Jun 8

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

8.8/10 Excellent! (1,059 reviews)

Rooftop bar was awesome!

Reviewed on Apr 29, 2026

The Wildwood Hotel

$314

per person

Jun 23 - Jun 25

found 2 hours ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

9.2/10 Wonderful! (1,625 reviews)

Another great stay at the Wildwood, clean rooms, comfy bed, really all you need for a quick trip out to visit friends!!

Reviewed on Apr 28, 2026

DoubleTree by Hilton Hotel St. Louis - Chesterfield

Save 100% on your flight

$357

per person

Jun 6 - Jun 8

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to St. Louis (STL)

8.6/10 Excellent! (1,002 reviews)

Room smelled musty. Hairs in shower.

Reviewed on Apr 27, 2026

Homewood Suites by Hilton St. Louis Westport

Save 100% on your flight

$611

per person

Jun 17 - Jun 20

found 1 day ago

Roundtrip flight included

Denver (DEN) to St. Louis (STL)

8.8/10 Excellent! (472 reviews)

Breakfast left a lot to be desired. No waffles and minimal options.

Reviewed on Apr 14, 2026

Up Up and Away Lodging

Save 100% on your flight

$897

per person

Jun 8 - Jun 13

found 11 hours ago

Roundtrip flight included

New York (NYC) to St. Louis (STL)

9.4/10 Exceptional! (27 reviews)

Yes! The room was beautiful. Very clean. Beth was an amazing hostess, and the breakfast hit the spot. I highly recommend the stay, and when I return, I will do the same B&B. Thanks, Beth!

Reviewed on Dec 5, 2025

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Where to stay in Southwest Illinois

Find the best Southwest Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southwest Illinois

Aerial view of the iconic Gateway Arch and Mississippi River with urban skyline and bridges, Downtown St. Louis, Missouri, United States.

Eastport

If you're spending some time in Eastport, Gateway Conference Center and Splash City Family Waterpark are top sights worth seeing.

Discover the most popular places to visit in Southwest Illinois

Southern Illinois University

4.5/5(175 reviews)

Take a campus tour or just explore the area of Southern Illinois University, during your trip to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.

Giant City State Park

4.5/5(80 reviews)

Walk amid mystical woodland, admire geological wonders, go horseback riding and camp in the wilderness in the spectacular countryside of Southwest Illinois.

Ferne Clyffe State Park

4.5/5(10 reviews)

You can take time to visit Ferne Clyffe State Park during your travels to Goreville. While you're in the area, wander around the parks.

Southwest Illinois Hotel Deals

Drury Inn & Suites St. Louis Fairview Heights

12 Ludwig Dr Fairview Heights IL

Fully refundableReserve now, pay when you stay

$108 nightly

$122 total

May 7 - May 8

Total with taxes and fees

9.2/10 Wonderful! (1,004 reviews)

Great hotel everything was perfect

Reviewed on Apr 25, 2026

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL

Fully refundableReserve now, pay when you stay

$59 nightly

$67 total

May 25 - May 26

Total with taxes and fees

6.8/10 (1,000 reviews)

Dirty, roaches, no elevator, bad smell

Reviewed on Apr 27, 2026

Drury Inn & Suites St. Louis O'Fallon, IL

1118 Central Park Drive O'Fallon IL

Fully refundableReserve now, pay when you stay

$106 nightly

$123 total

May 10 - May 11

Total with taxes and fees

9.6/10 Exceptional! (1,001 reviews)

The Staff was pretty helpful with answering questions that I needed answered

Reviewed on Apr 29, 2026

See all 757 properties in Southwest Illinois

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.