Title: Southwest Illinois Vacation Packages 2026 from $382 | Expedia.com [Southwest Illinois Travel Guide](https://expedia.com/Southwest-Illinois.dx6058943)[Hotels in Southwest Illinois](https://expedia.com/Southwest-Illinois-Hotels.d6058943.Travel-Guide-Hotels)[Vacation Rentals in Southwest Illinois](https://expedia.com/Southwest-Illinois-Vacation-Rentals.d6058943.Travel-Guide-VacationRentals)[Flights to Southwest Illinois](https://expedia.com/Cheap-Flights-To-Southwest-Illinois.d6058943.Travel-Guide-Flights)[Car Rentals in Southwest Illinois](https://expedia.com/Car-Rentals-In-Southwest-Illinois.d6058943.Car-Rental-Guide) ![](https://images.trvl-media.com/place/6058943/ba13542c-304d-47c2-bad4-d7c83a7389e4.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Southwest Illinois Vacations from $382 ## Book a Hotel + Flight or Car together to unlock savings Photo by Southernmost Illinois Tourism Bureau - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ### Your Southwest Illinois Vacation When it's time for your next epic adventure, our Southwest Illinois vacation packages are the answer. Culture and history are among the many things that make this destination such a special place. Begin your trip to Southwest Illinois with some time exploring [O'Fallon](https://www.expedia.com/OFallon.d7403.Destination-Travel-Guides) visiting popular sights like O'Fallon Family Sports Park and FanDuel Sportsbook and Horse Racing. [Marion](https://www.expedia.com/Marion.d2469.Destination-Travel-Guides) is another city that lures travelers from all over. Lake of Egypt and Crab Orchard National Wildlife Refuge are two of the top places to see in this destination. From the moment you book your Southwest Illinois vacation to the second you come back home, Expedia will be with you each step of the way. ## The Latest Southwest Illinois vacation packages Price found within the past 48 hours. Click for updated prices. ![Hilton Garden Inn Chesterfield](https://images.trvl-media.com/lodging/1000000/300000/297100/297075/40ccff19_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hilton Garden Inn Chesterfield Save 100% on your flight $382 per person May 22 - May 26 found 9 hours ago Roundtrip flight included Atlanta (ATL) to St. Louis (STL) 8.2/10 Very Good! (810 reviews) Room was clean. Had Netflix on tv Reviewed on Mar 16, 2026 ![The Wildwood Hotel](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/035dee6c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Wildwood Hotel Save 100% on your flight $475 per person May 22 - May 26 found 1 day ago Roundtrip flight included Atlanta (ATL) to St. Louis (STL) 9.2/10 Wonderful! (1,627 reviews) The breakfaat was average, thou fresh. There was enough street parking nearby, safe. Reviewed on Mar 30, 2026 ![The Cheshire](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/24983857_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Cheshire $555 per person May 22 - May 26 found 1 day ago Roundtrip flight included Atlanta (ATL) to St. Louis (STL) 8.6/10 Excellent! (1,011 reviews) It had unique decor which was fun. Staff was nice But the lights were broken and there was a leftover can under a chair Reviewed on Apr 1, 2026 ![Spacious 3-Bedroom with King Bed](https://images.trvl-media.com/lodging/110000000/109680000/109680000/109679988/f2203ae1_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Spacious 3-Bedroom with King Bed Central West End Save 100% on your flight $988 per person May 22 - May 26 found 1 day ago Roundtrip flight included Atlanta (ATL) to St. Louis (STL) 8.8/10 Excellent! (11 reviews) Clean room nice area Reviewed on Feb 1, 2026 ![HoteLumiere at the Arch - A Caesars Rewards Destination](https://images.trvl-media.com/lodging/2000000/1830000/1828900/1828851/96d30602_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### HoteLumiere at the Arch - A Caesars Rewards Destination Downtown St. Louis $429 per person May 22 - May 26 found 1 day ago Roundtrip flight included Atlanta (ATL) to St. Louis (STL) 6.8/10 (1,006 reviews) Definitely needs some updates and a little TLC Reviewed on Mar 9, 2026 Don't see what you're looking for? See all available trips from Columbus to Southwest Illinois [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-05-09/2026-05-16/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=STL&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## Where to stay in Southwest Illinois Find the best Southwest Illinois areas and neighborhoods for the activities you enjoy most. [Learn more about Southwest Illinois](https://expedia.com/Southwest-Illinois.dx6058943) ![Aerial view of the iconic Gateway Arch and Mississippi River with urban skyline and bridges, Downtown St. Louis, Missouri, United States.](https://images.trvl-media.com/place/919377102216814592/2a570671-3bfc-4dad-9a0b-0e4ddc9285a5.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Eastport If you're spending some time in Eastport, Gateway Conference Center and Splash City Family Waterpark are top sights worth seeing. [Find hotel + flight trips in Eastport](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Eastport&DestID=919377102216814592&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Uptown](https://images.trvl-media.com/place/7352/fbb86aa3-d773-435e-a9bc-ffeede69934f.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Uptown If you're spending some time in Uptown, Kruta Bakery and World's Largest Catsup Bottle are top sights worth seeing. [Find hotel + flight trips in Uptown](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Uptown&DestID=919374982262484992&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Drone panorama over St. Louis skyline and Mississippi River with Gateway Arch during daytime](https://images.trvl-media.com/place/553248634983325621/8f057763-d7fd-4b7e-8061-2d691c553399.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Alorton Alorton is well-liked for its restaurants. If you'd like to do some sightseeing in the greater East St. Louis area, you might plan a trip to Frank Holten State Recreation Area or Arsenal BG Ballpark. [Find hotel + flight trips in Alorton](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Alorton&DestID=553248634983325621&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Mulberry Hills While Mulberry Hills isn't home to many top sights, Gateway Conference Center and FanDuel Sportsbook and Horse Racing are some notable places to visit nearby. [Find hotel + flight trips in Mulberry Hills](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Mulberry%20Hills&DestID=919375590275092480&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![early morning Cityscape of St. Louis skyline in Missouri state](https://images.trvl-media.com/place/944688504424763392/cd15355a-21a6-4027-9677-02ea56793c54.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Historic Downtown Collinsville While Historic Downtown Collinsville isn't home to many top sights, Gateway Conference Center and Splash City Family Waterpark are some notable places to visit nearby. [Find hotel + flight trips in Historic Downtown Collinsville](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Historic%20Downtown%20Collinsville&DestID=944688504424763392&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ### Discover the most popular places to visit in Southwest Illinois ![Southern Illinois University](https://images.trvl-media.com/place/2248/9b5bcf3c-b257-45df-ada0-2586a8bac9f3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Southern Illinois University 4.5/5(175 reviews) Take a campus tour or just explore the area of Southern Illinois University, during your trip to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area. [](https://expedia.com/Southern-Illinois-University-Carbondale.d6091413.Vacation-Attraction) ![Giant City State Park](https://images.trvl-media.com/place/553248621532655802/76dd2265-5ec3-4420-847e-7befd5fc6f6d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Giant City State Park 4.5/5(80 reviews) Walk amid mystical woodland, admire geological wonders, go horseback riding and camp in the wilderness in the spectacular countryside of Southwest Illinois. [](https://expedia.com/Giant-City-State-Park-Illinois.d553248621532655802.Vacation-Attraction) ![Ferne Clyffe State Park](https://images.trvl-media.com/place/3000434209/f417d3fd-621e-4c7d-9679-a6bb9b1e6654.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Ferne Clyffe State Park 4.5/5(10 reviews) You can take time to visit Ferne Clyffe State Park during your travels to Goreville. While you're in the area, wander around the parks. [](https://expedia.com/Ferne-Clyffe-State-Park-Goreville.d553248635944111208.Vacation-Attraction) ## Southwest Illinois Hotel Deals ![Drury Inn & Suites St. Louis Fairview Heights](https://images.trvl-media.com/lodging/1000000/50000/41900/41802/91646e6b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Inn & Suites St. Louis Fairview Heights 12 Ludwig Dr Fairview Heights IL Fully refundableReserve now, pay when you stay $90 nightly $102 total Apr 16 - Apr 17 Total with taxes and fees 9.2/10 Wonderful! (1,011 reviews) Great room great breakfast very clean. Reviewed on Apr 9, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F16%2F2026&endDate=4%2F17%2F2026&selected=41802&PinnedHotelID=41802&HadPinnedHotel=true®ionId=6058943) ![Drury Inn & Suites St. Louis O'Fallon, IL](https://images.trvl-media.com/lodging/2000000/1550000/1544100/1544028/2e5b0061_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Inn & Suites St. Louis O'Fallon, IL 1118 Central Park Drive O'Fallon IL Fully refundableReserve now, pay when you stay $106 nightly $123 total May 10 - May 11 Total with taxes and fees 9.6/10 Exceptional! (1,002 reviews) The free breakfast & appetizers/dinner is wonderful♥️ The staff all seem happy & positive♥️ Very clean♥️ Reviewed on Apr 6, 2026 [](https://expedia.com/Hotel-Search?startDate=5%2F10%2F2026&endDate=5%2F11%2F2026&selected=1544028&PinnedHotelID=1544028&HadPinnedHotel=true®ionId=6058943) ![Drury Plaza Hotel Mt. Vernon](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/798d901b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Plaza Hotel Mt. Vernon 145 North 44th Street Mount Vernon IL Fully refundableReserve now, pay when you stay $103 nightly $116 total Apr 26 - Apr 27 Total with taxes and fees 9.6/10 Exceptional! (1,663 reviews) Checkin cas fast and room was clean Reviewed on Apr 5, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F26%2F2026&endDate=4%2F27%2F2026&selected=42021&PinnedHotelID=42021&HadPinnedHotel=true®ionId=6058943) [See all 752 properties in Southwest Illinois](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=4%2F10%2F2026&endDate=4%2F11%2F2026®ionId=6058943) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Southwest Illinois Vacation Packages ## Southwest Illinois Essential Information | Language | English | | --------------- | ------------------------------------- | | Currency | U.S dollars | | Closest Airport | Lambert-St. Louis Intl. Airport (STL) | ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) 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